WebIn some embodiments, the functional HSD17B13 genomic DNA and variant HSD17B13 genomic DNA molecules comprise or consist of at least about 1000 to at least about … Web26 nov. 2024 · Title: HSD17B13 and other liver fat-modulating genes predict development of hepatocellular carcinoma among HCV-positive cirrhotics with and without viral clearance …
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WebA common variant in hydroxysteroid 17-beta dehydrogenase 13 ( HSD17B13, rs72613567-A) is associated with a reduced risk of fibrosis in NAFLD, but the underlying mechanism (s) remains unclear. We investigated the effects of this variant in the human liver and in Hsd17b13 knockdown in mice by using a state-of-the-art metabolomics approach. Web1 jun. 2024 · Summary. 17β-HSDs are multifunctional enzymes and a large number of 17β-HSD inhibitors have been described in recent years ( Marchais-Oberwinkler et al., 2011 ). Increasing data demonstrate that HSD17B13, as a liver-specific LD protein, plays a critical role in the regulation of hepatic lipid homeostasis. ravishing addons
Phosphorylation of 17β-hydroxysteroid dehydrogenase 13 at …
Web26 nov. 2024 · The HSD17B13 rs72613567 variant is associated with lower levels of albuminuria in patients with biopsy-proven nonalcoholic fatty liver disease. Sun DQ, et al. Nutr Metab Cardiovasc Dis, 2024 Jun 7. PMID 33853719 Loss-of-function HSD17B13 variants, non-alcoholic steatohepatitis and adverse liver outcomes: Results from a multi … WebHSD17B13. 17β-Hydroxysteroid dehydrogenase type 13 also known as 17β-HSD type 13 is an enzyme that in humans is encoded by the HSD17B13 gene. [5] [6] 17β-HSD13 is … Web7 jan. 2024 · Recently, HSD17B13, a newly identified liver-enriched, hepatocyte-specific, lipid droplet-associated protein, has been reported to be strongly associated with the development and progression of NAFLD/NASH in both mice and humans. ravish got a clinometer