Bongkrekic acid-13c28
WebMolecular Weight: 486.61 (free acid) Molecular Formula: C 28 H 38 O 7 Solubility: Miscible with DMSO. Physical Properties: Solution at 1 mg/mL (2 mM) in 0.01M Tris buffer pH 7.5 (contains 1 mg net bongkrekic acid per mL) Purity: 97% by HPLC NMR (Conforms) Storage Temperature: -20° Stability: Stable for 1 year from date of purchase as supplied.
Bongkrekic acid-13c28
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Webthat bongkrekic acid is an inhibitor of oxidative phosphorylation in rat heart mitochondria, and that, unexpectedly, it also ac- celerated the oxidation of succinate and /3 … WebBongkrekic acid (BA) poisoning can be caused by eating spoiled or fermented foods contaminated with pseudomonas cocovenenans. Although some in vitro studies have …
WebNov 22, 2004 · Bongkrekic acid (1) 1 is a natural toxic antibiotic produced by the microorganism Pseudomonas cocovenenans.The high toxicity of 1 has been attributed to its affinity for the ATP/ADP translocator protein residing in the mitochondrial inner membrane, which prevents oxidative phosphorylation (IC 50 = 2 × 10 −8 M). 2 Furthermore, by … WebMar 2, 2024 · Bongkrekic acid is a heat-stable, highly unsaturated tricarboxylic fatty acid with a molecular weight of 486 kDa. Outbreaks …
WebMay 20, 1991 · Here we demonstrate that bongkrekic acid, a potent inhibitor of the mitochondrial ATP/ADP translocase, inhibits glucose-induced electrical activity in the pancreatic β-cell through the simulation of ATP-sensitive potassium channel (K-ATP-channel) activity. WebBongkrekic acid C28H38O7 - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville …
WebDec 14, 2024 · This genus of fungi produces lipophilic and highly toxic 3-nitropropionic acid (3-NPA), which causes severe encephalopathy (disease of the brain that alters brain function or structure). This explained the symptoms in AC which were like those caused by bongkrekic acid.
WebBongkrekic acid affects the liver, brain and kidneys, causing symptoms including lack of energy, dizziness, drowsiness, abdominal pain, vomiting etc. In severe cases, consuming food contaminated with Bongkrekic acid can be life threatening. What is SFA doing to reduce food safety risks from Bongkrekic Acid? gta 5 meth businessWebJan 19, 2024 · Bongkrekic acid is a heat-stable, highly unsaturated tricarboxylic fatty acid with a molecular weight of 486 kDa. Outbreaks have been reported from Indonesia, … fincen sar sharing guidanceWebMar 1, 1970 · The antibiotic bongkrekic acid is shown to inhibit the phosphorylation of added ADP coupled with either the reactions of the respiratory chain or the dismutation … fincen sars filingWebThe symptoms of 3-NPA toxicity in humans are similar to those for bongkrekic acid, as described regarding sugar cane poisoning in humans in China and Africa, including initial gastrointestinal symptoms with vomiting and diarrhea and progressing encephalopathy leading to coma and death (8,11,12). fincen sars formWebIso-bong: A versatile first synthesis of isobongkrekic acid (IBA) has been developed. Key steps include three different palladium cross-couplings and an asymmetric homopropargylation. In-depth synthetic studies reveal the challenges faced in generating the right geometry of each diene. Abstract gta 5 michael and amanda fanfictionWebSep 20, 2024 · Bongkrekic acid is produced by the bacterium, Burkholderia cocovenenans, which is ubiquitous in the soil and plants. It grows best at 37°C and can optimally produce bongkrekic acid at about 26°C. Bongkrekic acid is heat-stable and cannot be removed by washing. Patients suffering from bongkrekic acid poisoning may show symptoms … fincen sar form exampleWebAbstract An efficient total synthesis of (+)-bongkrekic acid, a potent apoptosis inhibitor, has been accomplished by employing a convergent strategy based on the Suzuki-Miyaura coupling of three fully functionalized segments. All Science Journal Classification (ASJC) codes Catalysis Organic Chemistry Fingerprint gta 5 michael amanda and tracey jimmy